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Slow Cooker Beef Brisket With Best Ever BBQ Sauce

Slow Cooker BBQ Beef Brisket

This Slow Cooker BBQ Beef Brisket is fall-apart tender, rich in smoky barbecue flavor, and incredibly easy to make. With a simple spice rub, homemade sauce, and hours of low, slow cooking, you get a hearty, satisfying meal that works for weeknights, holidays, or anytime you’re craving comfort food. Perfect sliced or shredded!
Prep Time 10 minutes
Cook Time 10 hours
Total Time 10 hours 10 minutes
Course Main Course
Cuisine American
Servings 6
Calories 422 kcal

Ingredients
  

For the Spice Rub

  • 1 tablespoon kosher salt
  • 1 teaspoon chili powder
  • ½ teaspoon garlic powder
  • ½ teaspoon ground mustard
  • ½ teaspoon onion powder
  • ¼ teaspoon celery seed optional
  • ¼ teaspoon freshly cracked black pepper

For the Sauce

  • 1 cup ketchup
  • 3 tablespoons brown sugar
  • 2 tablespoons apple cider vinegar or white vinegar
  • 1 tablespoon Worcestershire sauce
  • ½ teaspoon liquid smoke or ¼ tsp smoked paprika

Brisket

  • 3 to 4 lb beef brisket trimmed with fat cap left on top

Instructions
 

  • Rub the brisket with spice mixture. Cover and marinate overnight or for at least 1 hour.
  • Mix the sauce in a bowl. Adjust to taste and refrigerate until use.
  • Place the brisket fat side up in a slow cooker. Pour sauce over top.
  • Cover and cook on low for 10 hours, or until fork-tender.
  • Rest the brisket on a cutting board for 15–20 minutes before slicing or shredding.
  • Serve warm with extra sauce. Perfect in buns or plated with your favorite sides.

Notes

  • Use a 6-quart slow cooker for best results.
  • The brisket can be made a day ahead and reheated with better flavor.
  • Always slice against the grain for maximum tenderness.

Nutrition Information

Nutrient Per Serving (approx.)
Calories 422 kcal
Protein 48g
Total Fat 17g
Saturated Fat 6g
Carbohydrates 18g
Sugars 15g
Sodium 1750mg
Cholesterol 141mg
Fiber 0.3g
Potassium 910mg
Iron 5mg
Vitamin A 307 IU
Vitamin C 2 mg
Calcium 31 mg
Keyword Slow Cooker BBQ Beef Brisket