Preheat oven to 375°F (190°C). Line two baking sheets with parchment paper.
In a medium bowl, whisk together flour, pumpkin pie spice, baking soda, baking powder, and salt.
In a large bowl, beat softened butter with brown and white sugars until light and fluffy.
Add pumpkin puree, egg, and vanilla extract; mix until smooth.
Gradually combine the dry ingredients with the wet mixture until just smooth.
Fold in the chocolate chips gently.
Drop tablespoon-sized scoops of dough onto prepared baking sheets, spacing them about 2 inches apart.
Bake for 10-12 minutes until edges are golden brown. Let cool on baking sheets for a few minutes before transferring to a wire rack.